The prognosis of cryptogenic fibrosing alveolitis.
نویسندگان
چکیده
cases, 49-6 months in those dying from CFA only, and 48-4 months in those dying from CFA in whom the course of the illness was not influenced by corticosteroids. There was a wide variation in the natural course of the disorder, varying from death within a year of the onset of symptoms in five patients to prolonged survival with slow or arrested progress in four patients not treated with corticosteroids. Most patients died from CFA but five developed bronchial carcinoma and two died after lung biopsy.
منابع مشابه
Neutrophil activation in fibrosing alveolitis: a comparison of lone cryptogenic fibrosing alveolitis and systemic sclerosis.
Fibrosing alveolitis complicating systemic sclerosis (FASSc) carries a better prognosis than lone cryptogenic fibrosing alveolitis (CFA). We wanted to determine whether this improved prognosis is associated with differential neutrophil migration and activation in the lower respiratory tract. We therefore compared bronchoalveolar lavage (BAL) neutrophil numbers and levels of neutrophil-derived e...
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Received 12 January 1993 Returned to authors 22 July 1993 Revised version received 30 September 1993 Accepted for publication 6 December 1993 Abstract Background It has been hypothesised that cryptogenic fibrosing alveolitis has an immunological pathogenesis mediated by T lymphocytes. It is, however, recognised that patients may show dysregulation of the humoral immune system and that the prese...
متن کاملCirculating antibodies to lung protein(s) in patients with cryptogenic fibrosing alveolitis.
BACKGROUND It has been hypothesised that cryptogenic fibrosing alveolitis has an immunological pathogenesis mediated by T lymphocytes. It is, however, recognised that patients may show dysregulation of the humoral immune system and that the presence of large numbers of B lymphocytes in open lung biopsies may be associated with a poor prognosis. Evidence of a role for the humoral immune system i...
متن کاملHigh resolution computed tomographic assessment of asbestosis and cryptogenic fibrosing alveolitis: a comparative study.
BACKGROUND The aim of this study was to compare the distribution and configuration of lung opacities in patients with cryptogenic fibrosing alveolitis and asbestosis by high resolution computed tomography. METHODS Eighteen patients with cryptogenic fibrosing alveolitis and 24 with asbestosis were studied. Two independent observers assessed the type and distributions of opacities in the upper,...
متن کاملAccuracy of diagnostic coding of hospital admissions for cryptogenic fibrosing alveolitis.
To determine the accuracy of diagnostic coding of cryptogenic fibrosing alveolitis, the case notes of 166 admissions to four hospitals were reviewed. These consisted of all admissions that had been coded as "idiopathic fibrosing alveolitis" (ICD code 516.3: 97 admissions) or as "postinflammatory pulmonary fibrosis" (ICD code 515.9: 69 admissions). Of 88 available records of admissions coded as ...
متن کاملRising mortality from cryptogenic fibrosing alveolitis.
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ورودعنوان ژورنال:
- Thorax
دوره 27 5 شماره
صفحات -
تاریخ انتشار 1972